Neda Razavi's profile

Genomics and Personalized Medicine

Neda Razavi is the head of marketing at the Swiss healthcare company Roche Diagnostics. Neda Razavi is currently working toward a genomics and genetics certificate from Stanford University. Personalized medicine is influenced and often guided by breakthroughs in the genomics and genetics fields.

Personalized medicine enables healthcare professionals to precisely identify the right treatment for patients that will save time and cost both for the patient and the healthcare system. Genomic testing makes it possible to diagnose and assess risks for a number of diseases at an individual level. Genomics is the study of an individual’s entire or a section of the genome. It is often used to measure the effect the environment, heritage and lifestyle have on the gene, as well as the genetic sensitivity an individual may possess to certain medications or the risk an individual carries of developing certain genetic diseases. Understanding diseases at a genomic level is an important aspect of personalized medicine, in part because it is another way for healthcare practitioners to judge the benefits of certain medical treatments in much less time than by using trial and error. In addition, it allows early and precise detection of the diseases and root causes analysis.

Genomics also can reduce the side effects a patient must experience from untargeted treatments since the time to find medicines and therapies that work is shorter. The benefits of this approach are numerous. It also allows doctors to more quickly diagnose problems, and since certain diseases can be detected at a much earlier stage, the process can substantially improve patient outcomes. For example, in cancer treatment, understanding cancer at the genomic level allows healthcare practitioners to identify the gene or enzymatic pathway deficiencies and or mutations. Once correctly identifying the types of cancer mutations, doctors can prescribe a medicine that correctly targets the pathway/cells and achieve desirable results. Patients will show fewer side effects for the treatment when prescribed with personalized medicines, as personalized treatment may affect the healthy cells less and focus on cancer cells more.
Cancer is one of leading causes of death, affecting millions of lives annually. Cancer is a complex and heterogeneous condition. There are over 100 types of cancers impacting variety of organs and tissues in the body

However, cancer is a complex, extremely heterogeneous condition. There are over 100 types of cancers, located in different organs and tissues in human body. Some cancer types contain more specific classifications that allow scientists to categorize them based on their molecular subtype. Examples of this type of cancers are breast, colon, non-Hodgkin's lymphoma and lungs. Additionally, the expression of markers within the same tumor can change depending on the specific location or stage of cancer. Despite this complexity and variability, most types of cancer are treated with the same generic therapies. In the new precision medicine therapy, cancer is diagnosed using genome sequencing and imaging techniques to understand metabolomics, transcriptomics, proteomics deficiencies of the gene.
Genomics and Personalized Medicine
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Genomics and Personalized Medicine

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