Unraveling the Role of Protein Misfolding in Disease

The role of protein misfolding in disease is a burgeoning area of research, shedding light on the underlying mechanisms of various disorders. When proteins adopt incorrect conformations due to misfolding, they can form aggregates that disrupt cellular function and lead to pathological conditions. This phenomenon is implicated in a wide range of diseases, including neurodegenerative disorders like Alzheimer's and Parkinson's, as well as metabolic diseases, cancer, and autoimmune disorders. Understanding the link between protein misfolding and disease pathology is crucial for developing targeted therapies and diagnostic tools to combat these debilitating conditions and improve patient outcomes.